Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1008 | Pituitary - Clinical | ECE2017

Autoimmune hypophysitis with isolated corticotroph cell destruction due to Pembrolizumab treatment in a female patient with metastatic melanoma

Vasileiou Emmanouil , Tsentidis Charalampos , Bampilis Andreas , Ntova Vasiliki , Betsi Grigoria , Kassi Georgia

Introduction: Pembrolizumab is a programmed death receptor-1(PD-1)-blocking antibody, used in a variety of advanced malignant tumors with promising results, although adverse events are not rare.Case report: We present the case of an adult female, with negative personal and family history of autoimmune diseases, who developed malignant superficial melanoma of right wrist 6 years ago. She was initially treated with surgical resection (lesion and ipsilatera...